-
Ընկերության անվանումը
Letrozole(FeMara) CAS 112809-51-5
-
Աշխատանքային ոլորտ
Առանց փորձի, Ուսանողներ
-
Գրաֆիկ
Լրիվ աշխատանքային օր
-
Կրթություն
-
Փորձ
CAS No.112809-51-5
Chemical Name:Letrozole
SynonymsLETROZOL;FEMARA;LETRAZOLE;LetrozoleUsp28;Letrozole(FeMara);Letroz;etrozoL;Lelrozol;Lerozole;Laiquzuo
CBNumber:CB9286355
Molecular Formula:C17H11N5
Molecular Weight:285.3
Melting point 181-183°C
Boiling point 563.5±60.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >50mg/mL
pka 1.52±0.11(Predicted)
Uses
A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic
Uses
Letrozole has been used:
in organoid growth assay to determine its inhibitory capacity(48)
to investigate steroid receptor coactivator-1 (SRC-1) mediated endogenous estrogen regulation of hippocampal PSD-95(49)
to determine its effects on tumor-induced hyperalgesia(50)
for hormonal manipulation in rats(51)
to study its effects on lipocalin-2 (Lcn2)(52)
to determine its effects on mechanical hyperalgesia and aromatase expression(53) -
Նախընտրելի սեռ
-
Նախընտրելի տարիք
-
Նկարագիր
-
CAS No.112809-51-5
Chemical Name:Letrozole
SynonymsLETROZOL;FEMARA;LETRAZOLE;LetrozoleUsp28;Letrozole(FeMara);Letroz;etrozoL;Lelrozol;Lerozole;Laiquzuo
CBNumber:CB9286355
Molecular Formula:C17H11N5
Molecular Weight:285.3
Melting point 181-183°C
Boiling point 563.5±60.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >50mg/mL
pka 1.52±0.11(Predicted)
Uses
A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic
Uses
Letrozole has been used:
in organoid growth assay to determine its inhibitory capacity(48)
to investigate steroid receptor coactivator-1 (SRC-1) mediated endogenous estrogen regulation of hippocampal PSD-95(49)
to determine its effects on tumor-induced hyperalgesia(50)
for hormonal manipulation in rats(51)
to study its effects on lipocalin-2 (Lcn2)(52)
to determine its effects on mechanical hyperalgesia and aromatase expression(53)
