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Yohimbine hydrochloride (CAS 65-19-0)

  • Qanaqer Zeytun
  • 09/05/2024 05:56

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    Product Description
    Factory Source Yohimbine HCL CAS 65-19-0 White Aas Roids Powder USA Domestic/International
    Product Name:Yohimbine HCL
    Appearance :White to Yellow powder
    Cas:65-19-0
    molecular formula:C21H27N2O3
    molecular weight :355.4501
    Botanical Source:Corynante Yohimbe

    Yohimbine Hydrochloride is indicated as a sympathicolytic and mydriatic. It may have activity as an aphrodisiac. Impotence (not able to have erections)The way yohimbine works is not known for sure. It is thought, however, to work by increasing the body's production of certain chemicals that help produce erections. It does not work in all men who are impotent.
    New research that shows yohimbine hcl powder could be an herb with very effective antioxidant potential. Research shows it is a vasodilator, which means that it increases blood flow to the extremities and appendages.




    Yohimbine hydrochloride is an α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively). Yohimbine hydrochloride is an inhibitor of alpha2A-AR, alpha2B-AR and alpha2C-AR.
    References:
    Anesthesia induced by administration of xylazine hydrochloride alone or in combination with ketamine hydrochloride and reversal by administration of yohimbine hydrochloride in captive Axis deer (Axis axis). | Sontakke, SD., et al. 2007. Am J Vet Res. 68: 20-4. PMID: 17199414
    Platelet responsiveness to yohimbine hydrochloride and MRS2179 in the context of the interaction between collagen and epinephrine in acute coronary syndrome. | Lahiri, P., et al. 2009. Blood Cells Mol Dis. 43: 105-10. PMID: 19272818
    Yohimbine bioavailability in humans. | Guthrie, SK., et al. 1990. Eur J Clin Pharmacol. 39: 409-11. PMID: 2076728
    Yohimbine hydrochloride ameliorates collagen type-II-induced arthritis targeting oxidative stress and inflammatory cytokines in Wistar rats. | Neha, ., et al. 2017. Environ Toxicol. 32: 619-629. PMID: 27028940
    Antagonism of xylazine hydrochloride with yohimbine hydrochloride and 4-aminopyridine in captive wapiti. | Renecker, LA. and Olsen, CD. 1986. J Wildl Dis. 22: 91-6. PMID: 3005668
    The impact of Yohimbine-induced arousal on facets of behavioural impulsivity. | Herman, AM., et al. 2019. Psychopharmacology (Berl). 236: 1783-1795. PMID: 30635680
    Yohimbine hydrochloride inhibits benign prostatic hyperplasia by downregulating steroid 5 alpha -reductase type 2. | Zhao, Y., et al. 2021. Eur J Pharmacol. 908: 174334. PMID: 34265299
    Immobilization of coyotes with xylazine hydrochloride-ketamine hydrochloride and antagonism by yohimbine hydrochloride. | Kreeger, TJ. and Seal, US. 1986. J Wildl Dis. 22: 604-6. PMID: 3503155
    Yohimbine hydrochloride inhibits skin melanin synthesis by regulating wnt/ beta -catenin and p38/MAPK signal pathways. | Fu, T., et al. 2022. J Dermatol Sci. 107: 17-23. PMID: 35840473
    Yohimbine hydrochloride reversal of ketamine hydrochloride and xylazine hydrochloride immobilization of Bengal tigers and effects on hematology and serum chemistries. | Seal, US., et al. 1987. J Wildl Dis. 23: 296-300. PMID: 3586208
    Effect of caffeine sodium benzoate, ketamine hydrochloride, and yohimbine hydrochloride on xylazine hydrochloride-induced anorexia in white-tailed deer. | Van der Eems, K. and Brown, RD. 1986. J Wildl Dis. 22: 403-6. PMID: 3735587

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